Research on Schizophrenia Published by Researchers at Semmelweis University (Excitation/inhibition imbalance in schizophrenia: a meta-analysis of inhibitory and excitatory TMS-EMG paradigms).

Předmět:	RESEARCH personnel SCHIZOPHRENIA ARIPIPRAZOLE AMISULPRIDE TRANSCRANIAL magnetic stimulation
Zdroj:	Mental Health Weekly Digest; 7/5/2024, p584-584, 1p
Abstrakt:	A recent report from Semmelweis University discusses research on schizophrenia, specifically focusing on the potential model of cortical excitation-inhibition (E/I) imbalance in the pathophysiology of the disorder. The study utilized transcranial magnetic stimulation (TMS) and electromyography (EMG) to investigate inhibitory deficits in schizophrenia. The meta-analysis of 36 studies revealed a significant decrease in Short-Interval Intracortical Inhibition (SICI) in patients with schizophrenia, supporting the E/I imbalance hypothesis. The findings suggest that SICI may be a potential pathophysiological characteristic of the disorder. [Extracted from the article]
Databáze:	Complementary Index
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