Abstrakt: |
Researchers at the University of Birmingham have discovered a naturally occurring peptide called PEPITEM that shows promise as a new therapeutic for osteoporosis and other bone-related disorders. The research, funded by major grants from various organizations, demonstrates that PEPITEM enhances bone mineralization, formation, and strength, and can reverse bone loss in animal models of disease. PEPITEM regulates bone remodeling and has the potential to target the natural repair process compromised by age or inflammatory disease. The peptide also increases the maturation of osteoblasts, the cells responsible for bone formation, and reduces the number of osteoclasts, which break down bone. [Extracted from the article] |