| Autor: |
Prates Cordeiro, Fernanda, Moraes Marchiori, Luciana Lozza, Castro Teixeira, Denilson, Carvalho Andraus, Rodrigo Antonio, Célia Poli, Regina |
| Předmět: |
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| Zdroj: |
Noise & Health; Jan-Mar2024, Vol. 26 Issue 120, p44-50, 7p |
| Abstrakt: |
Objective: The aim of this study was to verify the association between the auditory handicap found in the Hearing Handicap Inventory for the Elderly-Screening Version (HHIE-S) questionnaire and hearing loss and the plasma levels of inflammatory biomarkers. Materials and Methods: Cross-sectional study with 76 participants, 67 (88%) females and 9 (12%) males, with a mean age of 70 years. Tonal threshold audiometry and self-assessment with HHIE-S questionnaire were performed to measure the plasma levels of interleukin-2 (IL-2), IL-4, IL-6, and IL-10; tumor necrosis factor alpha; and interferon gamma (IFN-γ) flow cytometry method. For all data analyzed, the significance level adopted was P < 0.05 and 95% confidence interval. Results: An inverse correlation was observed between the increase in plasma levels of IFN-γ and normal auditory handicap (P= 0.015; rs=-0.280). The severe handicap group showed an increase in the averages I (P=0.005; rs=0.350) and II (P=0.016; rs=0.368) in the right ear and the light/moderate handicap group increased the means I (P=0.027; rs=0.350) and II (P=0.046; rs=0.310) of the left ear. A statistically significant association was found between the speech recognition threshold (SRT) test results of the right ear and the severe handicap group (P= 0.002; rs=0.271). Conclusions: There was an association between the increase in plasma levels of IFN-γ and normal auditory handicap. Additionally, statistically significant associations were observed between the mild/moderate and severe handicap groups with the increase in hearing means and an increase in SRT associated with the severe handicap group. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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