Step away from depression—results from a multicenter randomized clinical trial with a pedometer intervention during and after inpatient treatment of depression.

Autor: Große, Julia, Huppertz, Charlotte, Röh, Astrid, Oertel, Viola, Andresen, Sara, Schade, Niklas, Goerke-Arndt, Franziska, Kastinger, Anna, Schoofs, Nikola, Thomann, Philipp Arthur, Henkel, Karsten, Malchow, Berend, Plag, Jens, Terziska, Aleksandra, Brand, Ralf, Helmig, Frank, Schorb, Alexander, Wedekind, Dirk, Jockers-Scherübl, Maria, Schneider, Frank
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Zdroj: European Archives of Psychiatry & Clinical Neuroscience; Apr2024, Vol. 274 Issue 3, p709-721, 13p
Abstrakt: Evidence for the effectiveness of physical activity (PA) in the treatment of depression prevails for outpatients with mild and moderate symptom levels. For inpatient treatment of severe depression, evidence-based effectiveness exists only for structured and supervised group PA interventions. The Step Away from Depression (SAD) study investigated the effectiveness of an individual pedometer intervention (PI) combined with an activity diary added to inpatient treatment as usual (TAU). In this multicenter randomized controlled trial, 192 patients were randomized to TAU or TAU plus PI. The two primary outcomes at discharge were depression—blindly rated with the Montgomery–Åsberg Depression Rating Scale (MADRS)—and average number of daily steps measured by accelerometers. Secondary outcomes were self-rated depression and PA, anxiety, remission and response rates. Multivariate analysis of variance (MANOVA) revealed no significant difference between both groups for depression and daily steps. Mean MADRS scores at baseline were 29.5 (SD = 8.3) for PI + TAU and 28.8 (SD = 8.1) for TAU and 16.4 (SD = 10.3) and 17.2 (SD = 9.9) at discharge, respectively. Daily steps rose from 6285 (SD = 2321) for PI + TAU and 6182 (SD = 2290) for TAU to 7248 (SD = 2939) and 7325 (SD = 3357). No differences emerged between groups in secondary outcomes. For severely depressed inpatients, a PI without supervision or further psychological interventions is not effective. Monitoring, social reinforcement and motivational strategies should be incorporated in PA interventions for this population to reach effectiveness. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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