Testicular Vascularization after Pediatric Inguinal Hernia Repair: A Systematic Review and Meta-Analysis.
| Autor: | Eurlings, Roxanne, Killaars, Rianne E. M., Visschers, Ruben G. J., van Gemert, Wim G. |
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| Předmět: |
MEDICAL information storage & retrieval systems
FERTILITY META-analysis CHI-squared test DESCRIPTIVE statistics SURGICAL complications SYSTEMATIC reviews MEDLINE INGUINAL hernia TESTIS BLOOD circulation MEDICAL databases ONLINE information services DATA analysis software CONFIDENCE intervals VASCULAR diseases DISEASE risk factors ADOLESCENCE CHILDREN |
| Zdroj: | Children; Apr2024, Vol. 11 Issue 4, p409, 14p |
| Abstrakt: | Background: The effect of pediatric inguinal hernia repair (IHR) on testicular vascularization remains unclear. Manipulating the spermatic cord during surgery may reduce blood flow due to edema and vasoconstriction. This can lead to testicular atrophy. The study aims to review current knowledge of testicular vascular impairment following IHR in children. Methods: A systematic literature search was conducted in PubMed/Medline, Embase, Cochrane Library, and Web of Science. Methodological quality was assessed using validated tools. Data were extracted, and a pooled data analysis was performed. Results: Ten studies were included in the systematic review. Six of these studies were eligible for meta-analysis. This revealed a significant decrease in testicular vascularization during the short-term follow-up (1 day–1 week) after IHR using the open surgical approach. This decrease was not present after laparoscopic intervention. There was no more increased resistance in the vessels at long-term follow-up (1 month–6 months), suggesting that the impaired vascularity is only temporary. Conclusions: There seems to be a short-term transient vascular impairment of the testis after open IHR in children. This might be of clinical relevance to prefer the laparoscopic approach for IHR in children, even though the open approach is the gold standard, in contrast to adult IHR. The impact on testicular function and sperm quality later in life remains unclear. Comparative studies of both techniques are needed to determine if there is a significant difference in testicular vascularity. Long-term studies are necessary to assess the impact of transiently reduced vascularity on sperm quality and fertility later in life. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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