| Autor: |
Mishra, Richa, Jamwal, Ashima, Gupta, Bishal, Kumar, Sudeep, Bharali, Abhijeet, Das, Parijat, Nath, Alok, Jain, Manoj, Neyaz, Zafar |
| Předmět: |
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| Zdroj: |
Lung India; Mar/Apr2024, Vol. 41 Issue 2, p130-134, 5p |
| Abstrakt: |
A 15-year-old boy presented with a sudden onset of breathlessness for 7 days, gradual loss of weight of 17.6 lbs over the last month and progressive hoarseness of voice for 7 months. The contrast-enhanced computed tomography (CECT) scan revealed a heterogeneously enhancing lesion in the anterior mediastinum with multiple discrete lymph nodes in the cervical and mediastinal locations. The GeneXpert MTB/RIF assay performed on the CT-guided biopsy of the mass was negative, but the culture for Mycobacterium tuberculosis was positive at 7 weeks of incubation. There was a suboptimal radiological response after 6 months of treatment. First-line drug susceptibility testing (DST) performed by line probe assay (LPA) on the positive culture detected high-level resistance to isoniazid. The treatment was modified as per DST results to which the patient responded well. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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