A COMPARATIVE CLINICAL STUDY BETWEEN 0.75% ROPIVACAINE VERSUS 0.75% ROPIVACAINE WITH BUPRENORPHINE FOR SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK UNDER ULTRASOUND GUIDANCE.

Autor: K. L., Rajeev Keerthi, D. S., Shashikiran, Aparajita, Shruti Bhushan, K. R., Madhu, Mahesh, Ullas
Předmět:
Zdroj: Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2024, Vol. 15 Issue 2, p1574-1584, 11p
Abstrakt: Background and Objectives: The use of ultrasound has gained popularity in the field of regional anaesthesia for upper limb surgical procedure, as it provides a direct visualization of the anatomic structures and allows a dynamic vision of needle movement and local anaesthetic spread. In the present study, we chose Buprenorphine as an adjuvant to Ropivacaine for ultrasound guided supraclavicular brachial plexus block based on hypothesis that the duration of action after single injection is limited when local anaesthetic alone is used and to prolong its effect, wide range of additives have been used in combination with local anesthetics to promote analgesia. Methodology: After obtaining ethical committee clearance, 60 patients of either sex in the age group of 25 to 60 years, with ASA status I and II, undergoing elective upper limb surgeries under ultrasound guided supraclavicular brachial plexus block, at Adichunchanagiri Institute of Medical Sciences, B.G. Nagara, Mandya, were randomly divided into two groups of 30 each. Group RP received Ropivacaine 0.75% 19 ml + Normal saline 1 ml (placebo). Group RB received Ropivacaine 0.75% 19 ml + Buprenorphine 75mcg (1ml). The time of onset and duration of sensory and motor blockade, duration of analgesia, occurrence of haemodynamic instability and adverse events were noted and the results were statistically analyzed, considering a P value of < 0.05 to be statistically significant. Results: The time of onset of sensory block in Group RP was of 6.7±0.51 minutes and in Group RB was of 4.533±0.57 minutes. The sensory block lasted for 334.33±15.01 minutes in Group RP and 606.17±88.29 minutes in Group RB. The onset of motor block in Group RP was 9.3±0.53 minutes and in Group RB was 6.1±0.54 minutes. The motor block lasted for 228.67±11.958 minutes in Group RP and 517.67±103.94 minutes in Group RB. The duration of analgesia in Group RP was 317.50±15.578 minutes and in Group RB was 687.83±19.059 minutes. There was statistically significant difference found between two groups with respect to onset of sensory and motor blockade, duration of sensory and motor blockade and duration of analgesia (with P value <0.001). None of the patients had any other complications in either group. Interpretation and Conclusion: Hence 0.75% Ropivacaine with buprenorphine 75mcg produced satisfactory sensory and motor blockade and also prolonged duration of analgesia when used for supraclavicular brachial plexus block under ultrasound guidance. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index