Cystoid Macular Edema following Treatment with Nanoparticle Albumin-Bound Paclitaxel and Atezolizumab for Metastatic Breast Cancer.

Autor:	Yamane, Hiroaki, Itagaki, Tomoko, Kajitani, Keiko, Koura, Yuji, Kawabuchi, Yoshiharu, Ohara, Masahiro
Předmět:	METASTATIC breast cancer MACULAR edema ATEZOLIZUMAB NANOPARTICLES PACLITAXEL
Zdroj:	Case Reports in Oncology; 2023, Vol. 16 Issue 1, p1121-1128, 8p
Abstrakt:	Cystoid macular edema (CME) is a rare side effect associated with chemotherapy. Although the development of CME has been reported to occur following treatment with taxane drugs, such as nanoparticle albumin-bound paclitaxel (Nab-PTX), the occurrence of CME with treatment with atezolizumab has not yet been reported. Here, we report the case of a 49-year-old woman who developed CME 19 months into chemotherapy with Nab-PTX and atezolizumab. Improvement was not achieved with steroid injections into the Tenon's sac, and Nab-PTX and atezolizumab treatments were ceased. One month later, there was subjective improvement in her symptoms. Although many reports have indicated that cessation of chemotherapy has successfully improved CME, a specific treatment for CME has not yet been established. Clinicians should be aware of the ophthalmologic side effects and offer immediate treatment if symptoms develop. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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