Studies from University of South China Describe New Findings in Breast Cancer (Impact of NDUFAF6 on breast cancer prognosis: linking mitochondrial regulation to immune response and PD-L1 expression).

Předmět:	IMMUNOREGULATION BREAST cancer prognosis BREAST cancer PROGRAMMED death-ligand 1 MITOCHONDRIA
Zdroj:	Women's Health Weekly; 2024, p1182-1182, 1p
Abstrakt:	A recent study conducted by researchers at the University of South China explores the role of the mitochondrial protein NDUFAF6 in breast cancer. The study analyzed breast cancer samples from various databases and experimental models, finding that NDUFAF6 is overexpressed in breast cancer patients and correlates with worse clinical features and prognosis. The protein is implicated in immune-related pathways and promotes PD-L1 expression by inhibiting the NRF2 signaling pathway. The study suggests that NDUFAF6 could serve as a potential prognostic biomarker and a target for immunotherapy in breast cancer. [Extracted from the article]
Databáze:	Complementary Index
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