Abstrakt: |
A recent report discusses research findings on cancer, highlighting the need for more effective therapeutic approaches to combat various types of cancer, especially advanced ones. The overexpression of tyrosine kinases, specifically VEGF and its receptors (VEGFR), is associated with cancer proliferation and angiogenesis. The report focuses on indole-containing compounds with potential antineoplastic and VEGFR inhibitory properties, summarizing recent analogs and highlighting the most important drugs and promising leads. The research concludes that these indolyl analogs show potential for inhibiting VEGFR and fighting cancer. [Extracted from the article] |