| Abstrakt: |
Background: The abbreviated biparametric MRI (bpMRI) uses T2 and diffusionweighted images without dynamic contrast-enhancement (DCE-MRI) to avoid the adverse effects, reduce testing time and cost, compared to multiparametric MRI (mpMRI). Its capability to detect prostate cancer with the Prostate Imaging and Reporting Data System version 2.1 needs more comprehensive studies. We aim To assess the reliability and diagnostic performance of the abbreviated bpMRI in the detection of prostate cancer using 3.0 tesla machine, compared to standard mpMRI using PI-RADS v2.1 Methods: Using 3.0T MRI machine, 180 biopsy-naïve patients suspected of prostatic cancer underwent an abbreviated bpMRI, then, the standard mpMRI was completed by DCE-MRI. Four experienced uroradiologists independently assessed each suspected PC lesion and the diagnostic performances of the two approaches were analyzed. Finally, transrectal US- guided targeted 12-core biopsies were performed for histopathology. Results: In this patient-based analysis, the mpMRI showed higher detection rates than the bpMRI approach, when considering category-three lesions as benign, with sensitivity, specificity, accuracy, positive and negative predictive values of 88.57%, 96%, 91.7%, 96.8%, 85.7% for the mpMRI protocol vs. 57.14%, 92%, 71.7%, 90.9%, 60.5% for the bpMRI protocol, respectively (P<0.001). ROC curve analysis exhibited a greater AUC for the full over the abbreviated protocol (0.937 vs. 0.883). However, this was not evident when considering the same category as malignant. Conclusions: When considering PI-RADS category three lesions as malignant, biparametric MRI could be considered as effective as multiparametric MRI. However, when considering category three lesions as benign, multiparametric MRI had a higher detection rate. [ABSTRACT FROM AUTHOR] |
