Birth History and Cardiovascular Disease Risk Among Youth With Significant Obesity.
| Autor: | Hurley, Sara K., Vizthum, Diane, Ducharme-Smith, Kirstie, Kamath-Rayne, Beena D., Brady, Tammy M. |
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| Předmět: |
HYPERTENSION risk factors
CARDIOVASCULAR diseases risk factors PREMATURE infants CHILDHOOD obesity FOOD consumption MULTIPLE regression analysis LEFT ventricular dysfunction LEFT ventricular hypertrophy GESTATIONAL age RISK assessment LOW birth weight DESCRIPTIVE statistics RESEARCH funding BODY mass index REPRODUCTIVE history DIETARY sodium DISEASE risk factors DISEASE complications |
| Zdroj: | Clinical Pediatrics; Mar2024, Vol. 63 Issue 3, p365-374, 10p |
| Abstrakt: | Children born prematurely have greater lifetime risk for hypertension. We aimed to determine (1) the association between prematurity and cardiovascular disease (CVD) risk factors among 90 children with obesity and elevated blood pressure and (2) if dietary sodium intake modified these associations. Multivariable regression analysis explored for associations between prematurity (<37 weeks gestation; early gestational age) and low birth weight (<2.5 kg) with hypertension, left ventricular mass index (LVMI), and left ventricular hypertrophy (LVH). Effect modification by dietary sodium intake was also explored. Patients were predominately male (60%), black (78%), adolescents (13.3 years), and with substantial obesity (body mass index: 36.5 kg/m2). Early gestational age/low birth weight was not an independent predictor for hypertension, LVMI, or LVH. There was no effect modification by sodium load. Our results suggest the increased CVD risk conferred by prematurity is less significant at certain cardiometabolic profiles. Promoting heart-healthy lifestyles to prevent pediatric obesity remains of utmost importance to foster cardiovascular health. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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