Utilization of Adipose-Derived Stem Cells in Cranial Nerve Regeneration: A Systematic Review.

Autor: Brown, Nolan J., Aguirre, Alex, Chee, Keanu, Himstead, Alex, Kortz, Mike
Předmět:
Zdroj: Journal of Neurological Surgery. Part B. Skull Base; 2024 Supplement, Vol. 85, pS1-S398, 398p
Abstrakt: This article, published in the Journal of Neurological Surgery, explores the use of adipose-derived stem cells (ADSCs) in the regeneration of cranial nerves. The researchers conducted a systematic review of 12 studies that investigated the role of ADSCs in specific neural injuries and their functional outcomes. The majority of the studies focused on the facial nerve, with others examining the optic, olfactory, and hypoglossal nerves. The results showed that ADSCs had positive effects on nerve regeneration, including increased myelinated fibers, improved muscle fiber diameter, and enhanced compound muscle action potentials. The researchers concluded that ADSCs have the potential to facilitate functional recovery of cranial nerves in both humans and animal models, and further investigation is needed to fully understand their clinical potential. [Extracted from the article]
Databáze: Complementary Index