The association between maternal colonization with Group B Streptococcus and infectious morbidity following transcervical Foley catheter-assisted labor induction.

Autor:	Ben-David, Alon, Meyer, Raanan, Mazaki-Tovi, Shali
Předmět:	HOST-bacteria relationships INDUCED labor (Obstetrics) CATHETER-related infections ACADEMIC medical centers COMMUNICABLE diseases NEONATAL sepsis CONFIDENCE intervals MULTIVARIATE analysis STREPTOCOCCAL diseases RETROSPECTIVE studies GESTATIONAL age MANN Whitney U Test URINARY catheters CERVIX uteri RISK assessment T-test (Statistics) PREGNANCY complications CHI-squared test DESCRIPTIVE statistics LABOR (Obstetrics) DATA analysis software LOGISTIC regression analysis ODDS ratio LONGITUDINAL method DISEASE risk factors
Zdroj:	Journal of Perinatal Medicine; Jan2024, Vol. 52 Issue 1, p65-70, 6p
Abstrakt:	To determine whether maternal colonization with Group B Streptococcus increases the risk for infectious morbidity following transcervical Foley catheter-assisted cervical ripening. A retrospective cohort study comparing infectious morbidity and other clinical outcomes by Group B Streptococcus colonization status between all women with singleton pregnancies who underwent Foley catheter-assisted cervical ripening labor induction at a single tertiary medical center during 2011–2021. Multivariable logistic regression explored the relationship between Group B Streptococcus colonization to adverse outcomes while adjusting for relevant clinical variables. A total of 4,409 women were included of whom 886 (20.1 %) were considered Group B Streptococcus carriers and 3,523 (79.9 %) were not. Suspected neonatal sepsis rate was similar between Group B Streptococcus carriers and non-carriers (5.2 vs. 5.0 %, respectively, p=0.78). Neonatal sepsis was confirmed in 7 (0.02 %) cases, all born to non-carriers. Group B Streptococcus carriers had a higher rate of maternal bacteremia compared to non-carriers (1.2 vs. 0.5 %, respectively, p=0.01). Group B Streptococcus colonization was independently associated with maternal bacteremia (adjusted odds ratio 3.05; 95 %CI 1.39, 6.66). Group B Streptococcus colonization among women undergoing Foley catheter-assisted cervical ripening does not seem to increase the risk for neonatal infection. However, higher rates of maternal bacteremia were detected. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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