| Autor: |
Ohya, Tomoyuki, Ichinose, Jun, Nagatsu, Kotaro, Sugo, Yumi, Ishioka, Noriko, Watabe, Hiroshi, Itoh, Masatoshi, Minegishi, Katsuyuki, Zhang, Ming-Rong |
| Předmět: |
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| Zdroj: |
Radiochimica Acta; Jan2024, Vol. 112 Issue 1, p37-43, 7p |
| Abstrakt: |
Rhodium-103m is one of the most attractive Auger electron emitters for internal radiotherapy. The half-life of 103mRh is relatively short (56.114 min). Therefore, it needs to be produced using a generator for clinical use. Most studies of 103Pd/103mRh generators using anion-exchange resins were carried out over 50 years ago. However, these resins are no longer commercially available. In the present study, we tested a 103Pd/103mRh generator using alternative anion-exchange resins (i.e., IRA904, IRA410, SA20A, and SA11AL). No-carrier-added 103Pd was used to make the generators. The 103mRh product was eluted from the generators using 6 mL of 0.1 M HCl with a flow rate 0.5 mL/min. The generator made from SA11AL showed good performance, with a yield of 39 %, an impurity level of 103Pd in the product of 0.29 %, and an operation time of 14 min. This makes this generator competitive with previously developed ones. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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