| Abstrakt: |
By firing polyurethane foam templates (STR brand, 12 pores per cm, China) with a porosity of ~65% at 1200°C, an open-pore calcium phosphate foam ceramic was obtained using a highly concentrated suspension based on synthetic hydroxyapatite heat-treated at 800°C, monocalcium phosphate monohydrate, and 0.8% polyvinyl alcohol. The resulting calcium phosphate foam ceramic after modification in SBF (simulated body fluid) solution concentrated by 5 times (SBF×5) consisted of β-tricalcium phosphate, β-calcium pyrophosphate, and biomimetic apatite and had a porosity of 53–59% and a static strength of ~0.05 MPa. The formed biomimetic apatite consisting of amorphous calcium phosphate Ca9(PO4)6 and apatite tricalcium phosphate Ca9HPO4(PO4)5OH crystallizes into β-tricalcium phosphate at 1200°C. Calcium phosphate foam ceramic modified with biomimetic apatite, after soaking in 5% hydroxyapatite gel and SBF×5, simulating a bone defect in vitro, in parallel with the formation of biomimetic apatite, is partially destroyed, which confirms its high bioactivity and resorbability. [ABSTRACT FROM AUTHOR] |
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