| Autor: |
McQuaid, Conor, Montagne, Axel |
| Předmět: |
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| Zdroj: |
Cardiovascular Research; 11/15/2023, Vol. 119 Issue 16, p2591-2593, 3p |
| Abstrakt: |
This article discusses the growing evidence that suggests SARS-CoV-2, the virus responsible for COVID-19, affects multiple organ systems in the body, including the vasculature. The authors focus on the role of pericytes, a type of cell found in the vasculature, in SARS-CoV-2 infection. They found that SARS-CoV-2 spike protein (Sp) localizes with pericytes in lung tissue of COVID-19 patients and that pericytes play a significant role in vascular dysfunction associated with the virus. The article highlights the complex interactions between pericytes and endothelial cells and suggests that targeting pericytes could be a promising therapeutic approach. However, further research is needed to fully understand the mechanisms of SARS-CoV-2 infection and its effects on the vasculature. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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