Abstrakt: |
Researchers at the Institute for Neuroscience have reported new findings on hormones and stress hormone receptor activation. The researchers have developed a highly potent and selective degrader, KH-103, which can deplete glucocorticoid receptors (GR) and prevent their overactivation. This degrader shows promise for therapeutic applications in stress-related psychiatry and beyond, offering a more nuanced understanding of GR functions. The research was published in Nature Communications and more information can be obtained from the Institute for Neuroscience. [Extracted from the article] |