Outcome and Brain Volume Changes over Time in Children with Autoimmune Encephalitis and MOG Antibodies.

Autor: Bertolini, A., Bartels, F., Wegener-Panzer, A., Cleaveland, R., Ullmann, F., Olive, G., Armangue, T., Häusler, M., Wendel, E. M., Knierim, E., Reiter-Fink, E., Breu, M., Marina, A. Della, Baumann, B. Tro, Reindl, M., Finke, C., Rostasy, K.
Předmět:
Zdroj: Neuropediatrics; 2023 Supplement 1, Vol. 54, pS1-S32, 32p
Abstrakt: This article, published in the journal Neuropediatrics, examines the outcome and brain volume changes over time in children with MOG-encephalitis (MOG-E), a rare clinical phenotype of MOGAD. The study included 21 children with MOG-E, who presented with symptoms such as encephalopathy, headache, focal neurological signs, seizures, or CSF pleocytosis. The results showed that the majority of children had a good clinical outcome, with resolution of MRI changes and decreasing MOG antibodies over time. However, brain volumetry measurements indicated a decrease in whole brain volume, particularly in gray matter, after onset. [Extracted from the article]
Databáze: Complementary Index