Synthesis of polyether macrodiolides based on acetylenic derivatives of (5Z,9Z)-tetradeca-5,9-diene-1,14-dioic acid.

Autor:	Islamov, I. I., Yusupova, A. V., D'yakonov, V. A., Dzhemilev, U. M.
Předmět:	DICARBOXYLIC acids OXIDATIVE coupling CARBODIIMIDES ACIDS ESTERIFICATION
Zdroj:	Russian Chemical Bulletin; Oct2023, Vol. 72 Issue 10, p2473-2483, 11p
Abstrakt:	The stereoselective synthesis of (5Z,9Z)-tetradeca-5,9-diene-1,14-dioic acid was carried out using Ti-catalyzed homo-cyclomagnesiation of 2-(hepta-5,6-dien-1-yloxy)tetrahydro-2H-pyran. Intermolecular esterification of this dicarboxylic acid with polyether acetylenic alcohols in the presence of carbodiimides was used to synthesize the corresponding monoesters and symmetric diesters. Using the intramolecular oxidative coupling of terminal triple bonds of the latter compounds, polyether macrodiolides containing 1Z,5Z-diene and 1,3-diyne fragments were synthesized. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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