Glaucoma in rural China (the Rural Epidemiology for Glaucoma in China (REG-China)): a national crosssectional study.

Autor: Yuanyuan Liu, Baoqun Yao, Xi Chen, Xueli Yang, Yong Liu, Zhenggao Xie, Xiaofeng Chen, Zhigang Yuan, Xingrong Wang, Dan Hu, Xiang Ma, Weiqi Gao, Ruifeng Wang, Yuzhong Yang, Song Chen, Jingkai Zhang, Zuoqing Song, Junsu Wang, Jing Wang, Jinyun Pei
Zdroj: British Journal of Ophthalmology; Oct2023, Vol. 107 Issue 10, p1458-1466, 9p
Abstrakt: Objective This study aimed to investigate the prevalence of glaucoma with associated factors in the rural populations of 10 provinces in China. Design A population-based cross-sectional study. Methods All participants aged 6 years or older from 10 provinces completed visual acuity testing, slitlamp examination, ophthalmoscopy and non-contact tonometry. Glaucoma suspects underwent fundus photography, Goldmann applanation tonometry, visual field testing and gonioscopy. Glaucoma was determined according to the International Society of Geographical and Epidemiological Ophthalmology classification scheme. Associations of demographics and medical factors with glaucoma were assessed using multiple logistic regression models. Results From June 2017 to October 2018, 48 398 of 52 041 participants were included in the final analyses. The age-standardised prevalence of glaucoma was 1.7% (95% CI 1.55% to 1.78%) among the participants older than 6 years, which was 2.1% (95% CI 1.93% to 2.23%) in participants aged over 40 years. The constituent ratios of glaucoma were: 44.4% primary angle-closure glaucoma (PACG), 34.7% primary openangle glaucoma, 2.6% congenital glaucoma and 18.3% other types of glaucoma. Increasing age, smoking, cerebral stroke, type 2 diabetes, higher education (college or more) and higher personal income were significant risk factors for PACG. The unilateral and bilateral blindness rates in the entire study population were 4.692% and 1.068%, respectively. A family history of glaucoma was a significant risk factor for the prevalence of glaucoma and blindness in at least one eye. Conclusions Rural populations have a high prevalence of glaucoma, which should be included in chronic disease management programmes in China for long-term care. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index