| Autor: |
de Boni, Laura, Odainic, Alexandru, Gancarczyk, Natalie, Kaluza, Luisa, Strassburg, Christian P., Kersting, Xenia A. K., Wüllner, Ullrich, Schmidt, Susanne V., Petzold, Gabor C. |
| Předmět: |
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| Zdroj: |
Neurological Research & Practice; 9/28/2023, Vol. 5 Issue 1, p1-4, 4p |
| Abstrakt: |
Headache is one of the most common neurological manifestations of COVID-19, but it is unclear whether chronic headache as a symptom of Post-COVID-19 is associated with ongoing CNS damage. We compared cerebrospinal fluid (CSF) levels of markers of CNS damage and inflammation in Post-COVID-19 patients with persistent headache to hospitalized acute COVID-19 patients with neurological symptoms and to non-COVID-19 disease-controls. CSF levels of neurofilament light chain, Ubiquitin carboxyl-terminal hydrolase L1 and Tau were similar in patients with persistent headache in post-COVID-19 compared to acute COVID-19 patients and all control groups. Levels of glial fibrillary astrocytic protein were lower in patients with persistent headache in post-COVID-19 compared to some control groups of patients with neurological disease. Therefore, our pilot study of CSF markers indicates that persistent post-COVID-19 headache is not a sign of underlying neuronal damage or glial activation. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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