The hereditary N363K POLE exonuclease mutant extends PPAP tumor spectrum to glioblastomas by causing DNA damage and aneuploidy in addition to increased mismatch mutagenicity.

Autor: Labrousse, Guillaume, Perre, Pierre Vande, Parra, Genis, Jaffrelot, Marion, Leroy, Laura, Chibon, Frederic, Escudie, Frederic, Selves, Janick, Hoffmann, Jean-Sebastien, Guimbaud, Rosine, Lutzmann, Malik
Zdroj: NAR Cancer; Jun2023, Vol. 5 Issue 2, p1-16, 16p
Databáze: Complementary Index