Calcifications in oral carcinomas: Depicts diversity of calcium in cancer biology!

Autor: Banerjee, Abhishek, Nandini, Doddabasavaiah Basavapur, Misra, Satya Ranjan, Chakraborty, Bidyut
Předmět:
Zdroj: Journal of Oral & Maxillofacial Pathology (0973029X); Apr-Jun2023, Vol. 27 Issue 2, p396-398, 3p
Abstrakt: Calcifications in the soft tissues can be accidental findings during diagnostic procedures. Oral squamous cell carcinoma (OSCC) forms the major percentage of oral malignancies; calcifications are rare findings in OSCC. Calcifications are seen as a result of necrosis, chronic inflammations as well as degenerative changes and imbalances of the local calcium and phosphorous environment. The presence of calcifications can be a prognostic marker, hypothesizing that the influx of calcium from hard tissues into the soft tissues, can probably determine the invasive nature and the destructive characteristics of the carcinoma; hence, detecting calcifications can help us in predicting the prognosis and spread of the malignancy. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index