| Abstrakt: |
Astrocytes are capable of responding to neurotransmitter release from nearby neurons with internal calcium elevation and subsequent release of a neuroactive transmitter, which in turn can modulate neurons at the synaptic cleft. A 01-01 Effect of chronic unpredictable mild stress (CUMS) and ketamine treatment on circRNAs express... Luiz Filipe Bastos Mendes 1, Lucas dos Santos da Silva 1, Luiza Marques Prates Behrens 2,... 1 Universidade Federal do Rio Grande do Sul, Centro de Biotecnologia, Porto Alegre, Brazil; 2... Major depressive disorder (MDD) is the psychiatric disorder that causes the greatest social and economic damage in the world, being thus a disorder of great interest to the scientific community. Neurons are specialized cells capable of communicating with other neurons and with other cells through synapses. The brains harvested and processed for Cresyl Violet and immunohistochemistry for neurons (NeuN) and astrocytes (GFAP). We find that TH SP + sp /VGLUT2 SP + sp neuron expression differs from TH SP + sp /VGLUT2 SP - sp cells, suggesting TH SP + sp /VGLUT2 SP + sp DA neurons are a distinct cell population. [Extracted from the article] |
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