| Autor: |
Bradley, T. R., Nelson, J. F. |
| Zdroj: |
Australian Journal of Experimental Biology & Medical Science; Aug1959, Vol. 37 Issue 4, p373-382, 10p |
| Abstrakt: |
Alloxan diabetes results in loss of weight and considerable mortality in litters of lactating rats. Insulin replacement restores near normal litter growth rates and decreases litter death rate to zero. Metabolism of rat mammary gland slices in vitro after alloxan treatment closely resembles that observed after hypophysectomy of lactating rats. Insulin replacement therapy in vivo corrects a biochemical lesion responsible for an abnormal production of lactic acid. Diabetes renders mammary gland slices more sensitive to insulin in vitro, an opposite effect to that observed following hypophysectomy of lactating rats. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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