COMPARATIVE ACCURACY OF ALTERNATIVE EARLY MEASURES OF RESIDUAL DISEASE AFTER CAR19 THERAPY OF RELAPSED/REFRACTORY LBCL.

Autor: Sworder, B. J., Alig, S. K., Shukla, N., Garofalo, A., Macaulay, C. W., Esfahani, M. Shahrokh, Olsen, M. N., Hamilton, J., Hosoya, H., Hamilton, M. P., Spiegel, J. Y., Baird, J. H., Carleton, M., Younes, S. F., Schroers‐Martin, J. G., Liu, C. L., Natkunam, Y., Majzner, R. G., Mackall, C. L., Miklos, D. B.
Předmět:
Zdroj: Hematological Oncology; Jun2023 Supplement 1, Vol. 41, p214-216, 3p
Abstrakt: B Conclusions: b Detection of ctDNA MRD using PhasED-Seq is prognostic for outcomes in rrLBCL patients undergoing CAR19 therapy, and has superior performance compared to CAPP-Seq and PET/CT. B Introduction: b Over half of relapsed/refractory large B-cell lymphoma (rrLBCL) patients receiving anti-CD19 chimeric antigen receptor (CAR19) T-cells experience subsequent relapse. [Extracted from the article]
Databáze: Complementary Index