Researchers from Augusta University Describe Findings in Gene Therapy (TCR T cells overexpressing c-Jun have better functionality with improved tumor infiltration and persistence in hepatocellular carcinoma).

Předmět:	T cells GENE therapy GENETIC overexpression T cell receptors
Zdroj:	Cancer Gene Therapy Week; 5/22/2023, p357-357, 1p
Abstrakt:	Keywords: Bioengineering; Biotechnology; Cancer; Carcinomas; Drugs and Therapies; Engineered T-Cells; Gene Therapy; Health and Medicine; Liver Cancer; Oncology; Tissue Engineering EN Bioengineering Biotechnology Cancer Carcinomas Drugs and Therapies Engineered T-Cells Gene Therapy Health and Medicine Liver Cancer Oncology Tissue Engineering 357 357 1 05/22/23 20230522 NES 230522 2023 MAY 25 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Gene Therapy Week -- New research on gene therapy is the subject of a new report. MethodsRecombinant lentiviral vectors (lv), expressing either the HLA-A2/AFP158-specific TCR or both the TCR and c-Jun (TCR-JUN), were constructed and used to transduce primary human T cells to generate the TCR or TCR-JUN T cells, respectively. [Extracted from the article]
Databáze:	Complementary Index
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