| Autor: |
Walters, M. R., Nemere, I. |
| Předmět: |
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| Zdroj: |
Cellular & Molecular Life Sciences; Sep2004, Vol. 61 Issue 18, p2309-2321, 13p, 3 Diagrams, 3 Charts |
| Abstrakt: |
Steroid hormones are now recognized to act through both nuclear and membrane-associated receptors. In this review we focus on receptors for estrogen and the vitamin D metabolite 1,25-dihydroxyvitamin D3. While the nuclear receptors are part of a ‘superfamily’ with common structural elements, membrane receptors are more diverse, ranging from variants of the nuclear forms to unrelated proteins. We conclude that both rapid (membrane-initiated) actions, as well as regulation of gene transcription, are necessary to explain the complex actions of steroid hormones on target cells. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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