| Autor: |
Bang-yong, WU, Hong-yan, YI, Yan-lin, MA, Yuan-hua, HUANG |
| Předmět: |
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| Zdroj: |
Journal of Hainan Medical University; Feb2023, Vol. 29 Issue 4, p69-73, 5p |
| Abstrakt: |
The activation and development of primordial follicles is the key to the maturation of female gametes. Premature ovarian insufficiency (POI) patients are unable to complete the primordial follicle activation and development due to follicular dormancy and unbalanced developmental regulation in the body, leading to female infertility. Ovarian tissue in vitro activation (IVA) technology has become a new way to solve the problem of patients who cannot auto-activate primordial follicles to obtain their own mature oocytes. In IVA research, signaling pathways such as PI3K/PTEN/Akt and Hippo have become the focus of current research. This review will describe the relevant research progress and clinical application of the IVA mechanism, and provide a reference for clinical research on ovarian tissue culture and activation in vitro. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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