Papillary dermal elastolysis histopathology mimicking folliculotropic mycosis fungoides.

Autor: Recio‐Monescillo, Miguel, Torre‐Castro, Juan, Manzanas, Carolina, Ruffin, Belen, Haya, Lara, Rodríguez Pinilla, Maria, Requena, Luis
Zdroj: Journal of Cutaneous Pathology; May2023, Vol. 50 Issue 5, p430-433, 4p, 3 Color Photographs
Abstrakt: Papillary dermal elastolysis is a rare acquired disease of the elastic tissue that mainly affects elderly women with a clinical presentation of small firm papules in the neck, the supraclavicular areas and the upper back. Histopathologically, it is characteristic to find a complete or almost complete absence of elastic fibers in the papillary dermis with stains such as orcein or Verhoeff‐Van Gieson. We present the case of an adult female patient presenting a clinical picture of years of evolution of elastic skin‐colored papules on her neck, occasionally pruritic. Two biopsies were performed. In one of them an inflammatory infiltrate affecting the hair follicles was observed, and she was diagnosed with mycosis fungoides. The other biopsy showed a total absence of elastic fibers in the papillary dermis and was diagnosed as elastolysis of the papillary dermis. In early stages of papillary dermal elastolysis, a perivascular and periadnexal lymphocytic inflammatory infiltrate has been described, as is the case described above. It is important for dermatopathologist to know this atypical but possible presentation, as it may require a differential diagnosis with other entities such as follicular mycosis fungoides. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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