Hedyocoronins A and B: two new oleanane saponins from the aerial parts of Hedyotis coronaria.

Autor: Pham, Nguyen-Kim-Tuyen, Thai, Hoang-Minh, Nguyen, Thi-Anh-Tuyet, Vo, Thi-Nga, Nguyen, Kim-Phi-Phung, Nguyen, Thi-Hoai-Thu
Předmět:
Zdroj: Natural Product Research; Apr2023, Vol. 37 Issue 8, p1292-1299, 8p
Abstrakt: Two new oleanane saponins, hedyocoronin A (1) and hedyocoronin B (2), were isolated from the aerial parts of Hedyotis coronaria (Kurz) Craib, Rubiaceae, collected at Da Oai district, Lam Dong province in Vietnam. Their chemical structures were elucidated by HR-MS, 1D and 2D-NMR spectra, along with the comparison with those reported in the literature. Compounds 1 and 2 showed weak cytotoxicity against KB and HeLa-S3 cancer cell lines with IC50 values of more than 54 µM. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index