Twelve-month efficacy of second-generation cryoballoon ablation for atrial fibrillation performed at community hospitals: results of the German register on cryoballoon ablation in local hospitals (regional).

Autor: Michaelsen, Jochen, Parade, Ulli, Bauerle, Hansjörg, Winter, Klaus-Dieter, Rauschenbach, Ulrich, Mischke, Karl, Schaefer, Carl, Gutleben, Klaus-Jürgen, Rana, Obaida R., Willich, Tobias, Schlößer, Marc, Rötzer, Alfons, Breithardt, Ole A., Middendorf, Stefan, Grove, Rainer, Mosa, Jörg, Krug, Joachim, Imnadze, Guram, Saygili, Erol, Hoffmann, Rainer
Zdroj: Journal of Interventional Cardiac Electrophysiology; Mar2023, Vol. 66 Issue 2, p417-425, 9p
Abstrakt: Background: The 12-month follow-up (F/U) efficacy of CBA PVI performed at community hospitals for treatment of symptomatic paroxysmal and persistent atrial fibrillation (AF) is unknown. This study determined the 12-month efficacy of pulmonary vein isolation (PVI) using cryoballoon ablation (CBA) performed at community hospitals with limited annual case numbers. Methods: This registry study included 983 consecutive patients (pts) from 19 hospitals, each with an annual procedural volume of < 100 PVI procedures/year. Pts underwent CBA PVI for paroxysmal AF (n = 520), persistent AF (n = 423), or redo PVI (n = 40). The primary endpoint was frequency of documented recurrent AF, the occurrence of atrial flutter or tachycardia following a 90-day period after the index ablation and up to 12 months. The frequency of repeat ablation was determined. Results: Isolation of all PVs was documented in 98% of pts at the end of the procedure. Twelve-month F/U data could be obtained in 916 pts. A 24-h ECG registration was performed in 641 pts (70.0%); in 107 pts (16.7%) of them, recurrent AF was documented. The primary endpoint was met in 193 F/U pts (21.1%). It occurred in 80/486 F/U pts with paroxysmal AF (16.4%), and in 107/390 F/U pts with persistent AF (27.4%). Redo PVI was performed in 71 pts (7.8%), and atrial flutter ablation was performed in 12 pts (1.4%). Conclusions: CBA PVI for paroxysmal or persistent AF can be performed at community hospitals with adequate rates of 12-month symptom freedom and arrhythmia recurrence. The study was registered at the German register of clinical studies (DRKS00016504). [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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