| Autor: |
Roland, J., Brézin, C., Cazenave, P.-A. |
| Předmět: |
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| Zdroj: |
Scandinavian Journal of Immunology; Sep1977, Vol. 6 Issue 9, p879-885, 7p |
| Abstrakt: |
Certain samples of hare IgG can combine with cross-linked anti-a2 antisera prepared in the a3jaH rabbit. This cross-reaction permitted the isolation, on hare IgG immunoadsorbent, of anti-a2 cross-reacting antibodies (anti-a2 (Lv) antibodies). The binding of labeled rabbit a2 IgG to insolubilized anti-a2 (Lv) antibodies is inhibited by al IgG, demonstrating a cross-reactivity with a2. The percentage of al IgG cross-reacting with anti-a2 antiserum (al (2) IgG) is about 0.5% of total a l IgG. The a1 (2) molecules represent another variant (or set of variants) of the al specificity. Demonstration of this variant of al IgG brings to seven the minimum number of described al variants, and its low concentration among al IgG (0.5%) is in favor of a larger number of variants of allotypic specificities. Arguments in favor of common ancestor gents for allotypy in lagomorphs are given. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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