| Abstrakt: |
Scilla siberica subsp. armena is known as Siberian Squill which is naturally distributed in Lebanon-Syria, Transcaucasus, and Turkey. It is a perennial bulbous plant with a short vegetation period from March to May. In this study, the antimicrobial, antioxidant, α-amylase, and α-glucosidase inhibitory activities of corm, leaf, and flower methanolic extracts were examined. The anatomy and morphology of the plant organs were investigated by light and electron microscopes. The anatomy of S. siberica subsp. armena was investigated for the first time by electron microscopy in this study. The corm, leaf, and flower methanolic extracts were assessed against E. coli ATCC 8739, S. aureus ATCC 6538, B. subtilis ATCC 19,659, C. albicans ATCC 10,231, C. krusei ATCC 14,243, and C. tropicalis ATCC 750. Among the extracts, that obtained from the blue pollen showed the best antimicrobial activity against C. tropicalis ATCC 750 strain with a MIC value of 312.5 µg/mL. The highest phenolic content was determined in leaf extract with 53.59211 µg GAE/mg extract value. The extract showed the best anti-lipid peroxidation activity with 376.69 µg/mL value. Using DPPH· and ABTS·+ tests, it was determined that the flower and leaf extracts have the best activity (IC50 = 756.13 μg/mL and IC50 = 94.07 μg/mL, respectively). The flower extract exhibited α-glucosidase inhibitory activity with the IC50 value of 5239 µg/mL. Based on the presented results of the in vitro antimicrobial, antioxidant, and antidiabetic activities of the S. siberica subsp. armena, we suggest that natural compounds from S. siberica subsp. armena are of potential use for the improvement of an antidiabetic, antioxidant, and antimicrobial agent. [ABSTRACT FROM AUTHOR] |
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