CLINICOPATHOLOGICAL STUDY OF POST-MENOPAUSAL BLEEDING IN A REGIONAL CANCER CENTRE IN NORTH INDIA.

Autor: Kotwal, Shilpii, Mukherjee, K., Reeta, Pande, S., Ghosh, R. R.
Předmět:
Zdroj: Indian Obstetrics & Gynaecology; 2022, Vol. 12 Issue 3, p31-35, 5p
Abstrakt: Background: Postmenopausal bleeding is a frequently encountered symptom in women seen in gynaecological office visits. A significant number of women have gynaecological malignancies like endometrial cancer and in low-and middle-income countries like India, carcinoma cervix still remains a leading cause of postmenopausal bleeding. Objectives: The purpose of our study was to analyse the age distribution and various causes of postmenopausal bleeding. Materials and methods: Fifty patients with the complaint of postmenopausal bleeding were included in this prospective study (August 2020 - July 2022). A detailed history, systemic and gynaecological examination was carried out on these patients during their first visit. Each patient underwent a Pap smear test, transvaginal ultrasound followed by endometrial biopsy and cervical biopsy where indicated. Results: Eighty percent of women in the study had benign lesions and 20% women showed malignant lesions. Endometrial histopathological examination revealed the benign conditions like endometrial atrophy (24%), atrophic vaginitis (16%), cystic glandular hyperplasia (10%), proliferative endometrium (8%), chronic endometritis (8%), endometrial hyperplasia (6%), endometrial polyps (6%) and fibroids in one (2%) patient. Among malignant lesions, cervical cancer was seen in 16% and endometrial cancers in 4% women. In majority of cases the cancers were of well differentiated variety. Conclusion: The common causes of postmenopausal bleeding are usually benign lesions. Detailed evaluation is often needed, to rule out other lethal causes like endometrial and cervical cancer (especially in our country), both of which classically present with postmenopausal bleeding. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index