| Autor: |
Houari Adli, Djallal Eddine, Ziani, Kaddour, Kourat, Dallal, Brahmi, Mostapha, Souidi, Sendous Adjila, Naar, Asma, Kahloula, Khaled, Slimani, Miloud |
| Předmět: |
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| Zdroj: |
Egyptian Academic Journal of Biological Sciences, C Physiology & Molecular Biology; Dec2022, Vol. 14 Issue 2, p403-413, 11p |
| Abstrakt: |
The objective of this study, on the one hand, is to evaluate the impact of aluminium intoxication, on the biochemical and hematological approaches of adult Wistar rats, on the other hand, to test the efficacy of Syzygium aromaticum essential oil (CEO) in restoring or not the harmful effects of the studied metal with a daily intraperitoneal injection of 0.1 ml CEO/kg. The extraction of the essential oil from S.aromaticum by hydro-distillation allowed us to obtain CEO with a yield of 10.18%. Chronic exposure to aluminum chloride at a concentration of 100mg/kg in rats decreased body and organ weights (Liver, Kidney) compared to controls. The intoxication also revealed a disruption of various biochemical parameters, including liver (TGO, TGP), and kidney (urea, creatinine) biochemical assays, Thus, the concentration of aluminium in the intoxicated group is high in the blood. Also, the results show a correction in the values of these parameters following the administration of CEO compared to those of exposed animals. CEO also corrected the shape of the affected blood cells after intoxication to aluminium. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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