| Autor: |
Matusz, Emily F., Price, Catherine C., Lamar, Melissa, Swenson, Rod, Au, Rhoda, Emrani, Sheina, Wasserman, Victor, Libon, David J., Thompson, Louisa I. |
| Předmět: |
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| Zdroj: |
Journal of the International Neuropsychological Society; Feb2023, Vol. 29 Issue 2, p148-158, 11p |
| Abstrakt: |
Objective: To determine whether the DCTclock can detect differences across groups of patients seen in the memory clinic for suspected dementia. Method: Patients (n = 123) were classified into the following groups: cognitively normal (CN), subtle cognitive impairment (SbCI), amnestic cognitive impairment (aMCI), and mixed/dysexecutive cognitive impairment (mx/dysMCI). Nine outcome variables included a combined command/copy total score and four command and four copy indices measuring drawing efficiency, simple/complex motor operations, information processing speed, and spatial reasoning. Results: Total combined command/copy score distinguished between groups in all comparisons with medium to large effects. The mx/dysMCI group had the lowest total combined command/copy scores out of all groups. The mx/dysMCI group scored lower than the CN group on all command indices (p < .050, all analyses); and lower than the SbCI group on drawing efficiency (p = .011). The aMCI group scored lower than the CN group on spatial reasoning (p = .019). Smaller effect sizes were obtained for the four copy indices. Conclusions: These results suggest that DCTclock command/copy parameters can dissociate CN, SbCI, and MCI subtypes. The larger effect sizes for command clock indices suggest these metrics are sensitive in detecting early cognitive decline. Additional research with a larger sample is warranted. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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