Is survival rate lower after breast cancer in deprived women according to disease stage?

Autor: Delacôte, Claire, Delacour-Billon, Solenne, Ayrault-Piault, Stéphanie, Tagri, Anne-Delphine, Rousseau, Gwenaëlle, Vincent, Mélissa, Amossé, Sophie, Delpierre, Cyrille, Cowppli-Bony, Anne, Molinié, Florence
Zdroj: British Journal of Cancer; Jan2023, Vol. 128 Issue 1, p63-70, 8p
Abstrakt: Background: Socioeconomic deprivation has been associated with lower breast cancer (BC) survival, but the influence of stage at diagnosis on this association merits further study. Our aim was to investigate this association using the Loire-Atlantique/Vendee Cancer Registry (France). Methods: Twelve-thousand seven-hundred thirty-eight women living in the area covered by the registry and diagnosed with invasive breast carcinoma between 2008 and 2015 were included in the study. They were censored at maximal 6 years. Deprivation was measured by the French European Deprivation Index. Excess hazard and net survival were estimated for deprivation level, stage and age at diagnosis using a flexible excess mortality hazard model. Results: After adjustment by stage, women living in the most deprived areas had a borderline non-significant higher excess mortality hazard (+25% (95% CI: −3%; +62%)) compared to those living in the least deprived areas. Stage-adjusted 5-year net survival differed significantly between these two subgroups (respectively, 88.2% (95% CI:85.2%-90.5%) and 92.5% (95% CI:90.6%-93.9%)). Conclusion: BC survival remained lower in deprived areas in France, despite universal access to cancer care. Intensification of prevention measures could help to reduce advanced BC, responsible for the majority of deaths from BC. A better understanding of remaining social disparities is crucial to implement specific interventions. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
Externí odkaz: