| Autor: |
Jamieson, Dana, Ladner, Kathryn, van den Brenk, H. A. S. |
| Zdroj: |
Australian Journal of Experimental Biology & Medical Science; Oct1963, Vol. 41 Issue 5, p491-497, 7p |
| Abstrakt: |
The article focuses on The article focuses on pulmonary damage due to high pressure oxygen breathing in rats. The sulphydryl and disulphide contents of rat lungs were measured before and after exposure of rats to oxygen at 5 atmospheres absolute (OHP). After 45 minutes at this pressure lung damage occurred, and a decrease in -SH groups together with an increase in -SS- groups was found, such that the -SH/-SS- ratio in the lung tissue was halved. Injections of pentobarbital sodium, which protect against OHP lung damage, reduce autooxidation of -SH content of lung homogenate exposed to air in vitro and also reduce -SH oxidation in lungs of OHP exposed rats. |
| Databáze: |
Complementary Index |
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