Neuro-Ophthalmic Literature Review.

Autor: Bellows, David A., Chen, John J., Cheng, Hui-Chen, Jindahra, Panitha, MacIntosh, Peter W., McClelland, Collin, Vaphiades, Michael S., Zhang, Xiaojun
Předmět:
Zdroj: Neuro-Ophthalmology; Dec2022, Vol. 46 Issue 6, p429-437, 9p
Abstrakt: The authors reviewed 53 charts of all patients diagnosed with biopsy-proven GCA for those who also presented with a new onset of Horner's syndrome at the time of GCA diagnosis and two patients were found. Fifty-three patients (42.1%) had 3.0 T MRI, and 73 patients (57.9%) had 1.5 T MRI. ICI-associated Guillain-Barré syndrome has a high fatality rate (six out of 31 patients [19%] in one series died of this irAE), and even patients whose symptoms do improve with immunomodulation often have residual weakness and/or sensory loss (in one series 68% of patients had residual symptoms). The area under the receiver operator characteristic curve was 0.531 for anti-recoverin, 0.479 for anti- -enolase, 0.489 for anti-CAII, 0.737 for anti-CRX/CORD2, 0.637 for anti-HSP60, and 0.664 for anti-aldolase C. A higher number of retinal antibodies was associated with autoimmune retinopathy (>=4 antibodies were seen in 32.6% of patients with autoimmune retinopathy, 5% of patients with RP, and 3% of controls). [Extracted from the article]
Databáze: Complementary Index
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