Antibacterial flavonoids from the fruits of Macaranga hurifolia.

Autor:	Pagna, Julio Issah Mawouma, Awazi, Tengu, Mbarga, Paul Etoga, Mbekou, Ines Michèle Kanko, Mkounga, Pierre, Fotie, Jean, Frese, Marcel, Fabrice, Fekam Boyom, Lenta, Bruno Ndjakou, Sewald, Norbert, Nkengfack, Ephrem Augustin
Předmět:	IN vitro studies FLAVONOIDS PHYTOCHEMICALS FRUIT DESCRIPTIVE statistics RESEARCH funding PLANT extracts MOLECULAR structure BIOLOGICAL assay ANTIBIOTICS
Zdroj:	Journal of Asian Natural Products Research; Nov2022, Vol. 24 Issue 11, p1041-1051, 11p
Abstrakt:	As part of our search for new secondary metabolites from Macaranga hurifolia Beille, a phytochemical investigation was carried out on the fruits that led to the isolation and characterization of two new prenylated flavonol derivatives named macafolias A (1) and B (2), along with five known compounds. Their chemical structures were established on the basis of extensive analysis of their 1–D and 2–D NMR (1H, 13C, APT, COSY, HSQC and HMBC) in conjunction with mass spectroscopy and by comparison with data from the literature. The in vitro assay of the antibacterial potency of the crude extract, fractions and some pure compounds were evaluated against a wide range of bacteria strains. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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