| Autor: |
McClelland, D. B. L., Shearman, D. J. C., Lai A Fat, R. F. M., Van Furth, R. |
| Předmět: |
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| Zdroj: |
Clinical & Experimental Immunology; Jan1976, Vol. 23 Issue 1, p20-27, 8p |
| Abstrakt: |
An in vitro culture technique has been used to study synthesis of proteins by biopsies of human gastrointestinal mucosa which were obtained at endoscopy or surgery from patients with biliary gastritis, atrophic gastritis, peptic ulcer, gastric cancer, coeliac disease, Crohn's disease and ulcerative colitis. As in normal mucosa, immunoglobulin synthesis was found in all sites, but marked increases, especially in lgG, were seen in biliary gastritis and ulcerative colitis. In untreated coeliac disease, synthesis of lgG and IgM was increased. Synthesis of complement components did not differ from that found in normal mucosa. Increased lysozyme synthesis was seen in Crohn's disease. This study shows that useful information may be acquired from short-term culture studies of the small biopsies obtained with fibre optic endoscopes. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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