ANTILYMPHOCYTE SERUM: STUDIES OF THE SPECIFICITY OF THE ROSETTE-INHIBITING ANTIBODY IN RABBIT ANTI-MOUSE ALS.

Autor: Morton, H., Hegh, V., Clunie, G. J. A.
Zdroj: Australian Journal of Experimental Biology & Medical Science; Oct1975, Vol. 53 Issue 5, p373-380, 8p
Abstrakt: This article focuses on antilymphocyte serum. The immunosuppressive activity of ALS appears to result from a selective depletion of lymphocytes of the recirculating pool, but the precise mechanism of this action is still not clear. Since the rosette inhibition test forms a reliable in vitro assay for the immunosuppressive action of ALS, it seems possible that the rosette-inhibiting antibody may also be the agent directed against recirculating lymphocytes in vivo. This series of experiments with rabbit anti-mouse ALS has been designed to investigate this postulate.
Databáze: Complementary Index