| Autor: |
Maluish, Annette E., Koppi, Thelma A., Harper, Jacqueline J., Halliday, W. J. |
| Zdroj: |
Australian Journal of Experimental Biology & Medical Science; Oct1980, Vol. 58 Issue 5, p449-456, 8p |
| Abstrakt: |
The ability of tumour extracts to augment E-rosette formation by cancer patients' lymphocytes was demonstrated for colorectal carcinoma, breast carcinoma and melanoma. Positive augmentation reactions were obtained with 14 of 20 patients tested with extracts related to their own tumour types. Some lack of specificity was suggested by 5 positive reactions in hie same patients tested with unrelated extracts. No false positives were found in normal subjects. The technique is simple, rapid and appears to depend on tumour-associated antigens in the extracts. Simultaneous leucocyte adherence inhibition tests on split samples of blood had a high degree of sensitivity and specificity, confirming the potential reactivity of the leucocytes and extracts used. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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