Higher habitual dietary flavonoid intake associates with lower central blood pressure and arterial stiffness in healthy older adults.
| Autor: | Parmenter, Benjamin H., Croft, Kevin D., Cribb, Lachlan, Cooke, Matthew B., Bondonno, Catherine P., Lea, Ana, McPhee, Grace M., Komanduri, Mrudhula, Nolidin, Karen, Savage, Karen, Pase, Matthew P., Hodgson, Jonathan M., Stough, Con, Bondonno, Nicola P. |
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| Předmět: |
ATHEROSCLEROSIS prevention
FOOD habits HYPERTENSION LIFESTYLES FLAVONOIDS CONFIDENCE intervals CROSS-sectional method SYSTOLIC blood pressure GLYCOSIDES ISOFLAVONES TANNINS NUTRITIONAL requirements ARTERIAL diseases FLAVONOLS QUESTIONNAIRES DESCRIPTIVE statistics BLOOD pressure measurement HEMODYNAMICS FOOD quality FLAVANONES BIOLOGICAL pigments |
| Zdroj: | British Journal of Nutrition; 7/28/2022, Vol. 128 Issue 2, p279-289, 11p |
| Abstrakt: | Flavonoids have shown anti-hypertensive and anti-atherosclerotic properties: the impact of habitual flavonoid intake on vascular function, central haemodynamics and arterial stiffness may be important. We investigated the relationship between habitual flavonoid consumption and measures of central blood pressure and arterial stiffness. We performed cross-sectional analysis of 381 non-smoking healthy older adults (mean age 66·0 (sd 4·1) years; BMI, 26·4 (sd 4·41) kg/m2; 41 % male) recruited as part of the Australian Research Council Longevity Intervention study. Flavonoid intake (i.e. flavonols, flavones, flavanones, anthocyanins, isoflavones, flavan-3-ol monomers, proanthocyanidins, theaflavins/thearubigins and total consumption) was estimated from FFQ using the US Department of Agriculture food composition databases. Measures of central haemodynamics and arterial stiffness included systolic blood pressure (cSBP), diastolic blood pressure (cDBP), mean arterial pressure (cMAP) and augmentation index (cAIx). After adjusting for demographic and lifestyle confounders, each sd/d higher intake of anthocyanins ((sd 44·3) mg/d) was associated with significantly lower cDBP (−1·56 mmHg, 95 % CI −2·65, −0·48) and cMAP (−1·62 mmHg, 95 % CI −2·82, −0·41). Similarly, each sd/d higher intake of flavanones ((sd 19·5) mg/d) was associated with ~1 % lower cAIx (−0·93 %, 95 % CI −1·77, −0·09). These associations remained significant after additional adjustment for (1) a dietary quality score and (2) other major nutrients that may affect blood pressure or arterial stiffness (i.e. Na, K, Ca, Mg, n-3, total protein and fibre). This study suggests a possible benefit of dietary anthocyanin and flavanone intake on central haemodynamics and arterial stiffness; these findings require corroboration in further research. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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