| Autor: |
Nayakar, B. M. S. R., S., Samarth, B. G., Shivakumar |
| Předmět: |
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| Zdroj: |
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2022, Vol. 13 Issue 1, p627-633, 7p |
| Abstrakt: |
Introduction: Heart failure (HF) is a clinical syndrome that occurs in patients who, because of an inherited or acquired abnormality of cardiac structure and or function, develop a constellation of clinical symptoms (dyspnea and fatigue) and signs (edema and rales) that lead to frequenthospitalizations, a poor quality of life, and a shortened life expectancy. Heart failure is the leading cause of hospitalization in people older than. Materials and Methods: This is an observational study. This study is done in the department of General Medicine in Osmania General Hospital Hyderabad with tertiary care facilities. All patients who are admitted with symptoms and signs of Heart Failure in the wards like Intensive Care Unit, Acute Medical Care, Intensive Cardiac Care unit, Medical Wards, Cardiac Wards both paid and general rooms were recruited in the study. The sample size was 100 patients after evaluation by clinical and 2D echocardiography findings. Patients with signs and symptoms of Heart Failure andby satisfying inclusion and exclusion criteria were recruited. Those who were fit for dissertation were recruited in the study after informed consent. Results: In the present study 38.3 % were males had history of CAD compared to 22.6 % females there was no statistically significant difference between gender and history of CAD p >0.05. 34 % were males had history of DM compared to 52.8 % females there was no statistically significant difference between gender and history of DM p >0.05. 68.1 % were males had history of HTN compared to 73.6 % females there was no statistically significant difference between gender and history of HTN p >0.05. 0 % were males had history of HF compared to 5.7 % females there was no statistically significant difference between gender and history of HF p >0.05. Conclusions: This finding of excessive uric acid levels in chronic heart failure has lead to the recognition of association between heart failure and chronic inflammation thereby contributing to the oxidative damage to the myocardium. Increased UA in the circulation of HF patients may result from an increased generation of UA, a decreased excretion of UA, or a combination of both; however, overproduction of UA appears to be the dominate factor accounting for elevated UA levels in CHF. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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