| Autor: |
Froelich, Matthias F., Capoluongo, Ettore, Kovacs, Zsolt, Patton, Simon J., Lianidou, Evi S., Haselmann, Verena |
| Předmět: |
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| Zdroj: |
Clinical Chemistry & Laboratory Medicine; May2022, Vol. 60 Issue 6, p821-829, 9p |
| Abstrakt: |
These proof-of-principle studies have opened a new diagnostic field with a high potential to improve cancer screening and foster earlier diagnosis of cancer. In detail, instead of relying on fixed time intervals and pre-defined diagnostic procedures, individualization of the diagnostic modalities requires an adaptation and refinement of diagnostic procedures depending on an integrative evaluation of all diagnostic findings and stratification for the next diagnostic steps and time points. Nevertheless, the study has proved that by combing different types of cancers, the PPV can be increased from 0.8 to 7% for an individual type of cancer, and to 18.6% when applied as a pan-cancer test. They combined LB with classical protein tumor markers as a pan-cancer screening test including eight common cancer entities for early detection and localization of cancer. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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