| Autor: |
Ahmed, Muna R., Salih, Warqaa Y. |
| Předmět: |
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| Zdroj: |
Iraqi Journal of Community Medicine; Jan-Jun2021, Vol. 34 Issue 1, p37-41, 5p |
| Abstrakt: |
Background: Hepatitis C virus (HCV) genotypes have been shown to be differently distributed between distinct geographical areas. Information's regarding hepatitis C genotypes and subtypes distribution in Al-Nasiriya city are not well known. Objectives: The objectives of this study were to determine the frequency of various HCV genotypes in Al-Nasiriya city and the demographic and the risk factors associated with HCV transmission among Al-Nasiriya city population. Methods: Blood samples were collected from 200 patients with chronic HCV infection who were referred from Al-Nasiriya city to the digestive disease department of Al-Yarmouk Hospital during the period from February 2019 to December 2020. Patients were screened for HCV antibodies using an enzyme-linked immunosorbent assay test. Quantitation of the HCV viral load and genotype were assessed using polymerase chain reaction (PCR). Results: This study revealed that the most common HCV genotype was 1a (HCV-1a) with rate of 63% while (HCV-1d) showed 1.5% and (HCV-4) was 35.5%. Also the frequency of infection among females was more than males as (37.5% and 25.5%) respectively, while hemodialysis process among other transmission risk factors, increase transmission of HCV-1a infection. Conclusions: HCV-1a is the most predominance genotype in these patients, with more prevalent in female than male over 20 years old and hemodialysis is the most risk factor in their transmission. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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