Variants of Concern Are Overrepresented Among Postvaccination Breakthrough Infections of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Washington State.

Autor: McEwen, Abbye E, Cohen, Seth, Bryson-Cahn, Chloe, Liu, Catherine, Pergam, Steven A, Lynch, John, Schippers, Adrienne, Strand, Kathy, Whimbey, Estella, Mani, Nandita S, Zelikoff, Allison J, Makarewicz, Vanessa A, Brown, Elizabeth R, Bakhash, Shah A Mohamed, Baker, Noah R, Castor, Jared, Livingston, Robert J, Huang, Meei-Li, Jerome, Keith R, Greninger, Alexander L
Předmět:
Zdroj: Clinical Infectious Diseases; 3/15/2022, Vol. 74 Issue 6, p1089-1092, 4p
Abstrakt: Across 20 vaccine breakthrough cases detected at our institution, all 20 (100%) infections were due to variants of concern (VOCs) and had a median Ct of 20.2 (IQR, 17.1–23.3). When compared with 5174 contemporaneous samples sequenced in our laboratory, VOCs were significantly enriched among breakthrough infections (P <.05). [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index